Iron and iron chelating agents modulateMycobacterium tuberculosisgrowth and monocyte-macrophage viability and effector functions
نویسندگان
چکیده
منابع مشابه
petrology and geochemistry of khar-bash (western shahrood) and its relation ship to iron mineralization
منطقه مورد مطالعه در 23 کیلومتری جنوب غرب شهرستاشاهرود قرار دارد که در نقشه 100000/1 شاهرود قرار گرفته است.ناحیه مورد مطالعه در تقسیمات ساختاری ایران بخشی از زون البرز شرقی است . در طی سنوزوئیک این زون به شدت تحت تأثیر فازهای کوهزایی آلپی قرار گرفته و فعالیت های آتشفشانی انوسن در قسمت های غربی آن دیده می شود . از نظر ترکیب سنگ شناسی منطقه مورد مطالعه متنوع و بیشتر شامل سنگ های رسوبی مانند : آ...
15 صفحه اولIron chelating agents for treating malaria.
BACKGROUND Researchers are exploring the effects of adding treatments to the main antimalarial regimens in an attempt to reduce mortality from Plasmodium falciparum. Iron chelation is one potential chemotherapeutic adjuvant treatment. Before advocating adjunctive therapy, the effects of iron chelators in improving patient outcomes need to be examined. OBJECTIVES To assess the effects of iron-...
متن کاملSynthetic chelating agents in iron metabolism.
Iron in man is held within the cells incorporated in organic complex molecules, either as functional iron, i.e., hemoglobin and tissue enzymes, or as storage iron, i.e., ferritin and hemosiderin. Owing to the requirements of the erythroid marrow in particular, large amounts of iron must constantly pass from one cell to another through the plasma. This plasma transport is brought about by a #3gl...
متن کاملUsing Iron-Chelating Agents in Critically Ill Patients with Iron Overload. Fact or Fiction?
Recently, some evidence has shown that the failure of iron homeostasis may occur in critically ill patients and can lead to iron overload. Elevated ferritin levels as a body iron burden index in critically ill patients may be associated with depressed level of consciousness and greater mortality. However, the necessity of using iron-chelating agents in clinical situation is still unknown for th...
متن کاملManagement of transfusional iron overload – differential properties and efficacy of iron chelating agents
Regular red cell transfusion therapy ameliorates disease-related morbidity and can be lifesaving in patients with various hematological disorders. Transfusion therapy, however, causes progressive iron loading, which, if untreated, results in endocrinopathies, cardiac arrhythmias and congestive heart failure, hepatic fibrosis, and premature death. Iron chelation therapy is used to prevent iron l...
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ژورنال
عنوان ژورنال: FEMS Immunology & Medical Microbiology
سال: 2005
ISSN: 0928-8244,1574-695X
DOI: 10.1016/j.femsim.2005.02.007